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发布日期:2023-07-28    作者:     来源:     点击:

报告人简介:焦建伟 中国科学院动物研究所研究员、博士研究生导师,“国家杰青”万人领军人才”、中科院百人计划”、国家重点研发计划首席科学家。主要研究方向神经干细胞分化的机制研究micoRNA或表观遗传分子在神经发育中的作用以及神经干细胞的重编程研究。

报告内容简介:The mammalian brain contains millions of neurons and glial cells. Normal cerebral brain development plays an important role in controlling behavior, learning and cognition. During neurogenesis, neural progenitor cells (NPCs) proliferate and differentiate into neurons of cortical layers, which are precisely controlled by various intracellular and extracellular signaling pathways. NPCs of the brain are mainly PAX6-positive apical progenitor cells and TBR2-positive basal progenitor cells. Although more and more molecules are reported involved in the proliferation of progenitor cells, how neurogenesis is regulated by epigenetic factors during the embryonic development of the cerebral cortex remains largely to be investigated. Here, we found a series of epigenetic molecules and modifications are essential for the proliferation and self-renewal of neural stem cells.


报告地点:腾讯会议(会议号:172 612 802)


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